Iinzuzo ezifihliweyo zenikotini: isixhasi esingaqondakaliyo?

Inikotini, into abantu abayithandayo nabayithiyileyo, kudala ibethelelwa kwintsika yehlazo empilweni. Ngokwembono yoluntu, inxulunyaniswe ngokusondeleyo namagama awoyikisayo afana nomhlaza wemiphunga kunye nesifo sentliziyo. Kodwa emva kolu luvo lumnyama-namhlophe, uluntu lwezenzululwazi lutyhila inyani eyothusayo: inikotini ngokwayo inokuba sisiphuculi sokuqonda esingaqondwa kakhulu.

Xa sibekela bucala izithako eziyingozi zecuba size sijonge inikotini iyodwa, siya kufumanisa ukuba impembelelo yayo engqondweni intsonkothe ​​ngakumbi kunokuba besicinga. INicotine inokudlula ngokukhawuleza kwisithintelo segazi-ingqondo kwaye ibophe kwi-acetylcholine receptors kwingqondo. Le ndlela yokusebenza ifana ngokumangalisayo nomgaqo we-Alzheimer's drug. Uphononongo lubonise ukuba i-nicotine inokuphucula kakhulu ingqalelo, inkumbulo yokusebenza kunye nokuguquguquka kwengqondo. Ezi zinto zifunyanisiweyo zitshintsha indlela inzululwazi eziqonda ngayo inikotini.

Kwizifundo zeklinikhi, inikotini ibonise amandla okuphucula izifo ze-neurodeergenerative ezifana nesifo sika-Parkinson kunye nesifo se-Alzheimer. I-Nicotine patches isetyenziselwe ukunyanga ukuphazamiseka kwengqondo encinci kwaye ibonise iziphumo ezilungileyo ekuphuculeni imemori kunye nomsebenzi wokulawula. Okona kumangalisa ngakumbi kukuba inikotini ikwabonakalise ukukhululeka kweempawu kwizigulana ezinengxaki yokungahoywa kwe-hyperactivity disorder (ADHD).

Kodwa uphuculo lwengqondo yenikotini likrele elintlangothi-mbini. Ukuba likhoboka layo akunakungahoywa. Ukusetyenziswa kwexesha elide kunokukhokelela kwiinguqu kwi-receptors sensitivity kunye nokuxhomekeka. Oku kuxhomekeka akubonakali nje kuphela kwinqanaba lomzimba, kodwa kunempembelelo enzulu ngakumbi kwimeko yengqondo yomsebenzisi kunye neendlela zokuziphatha.

Ngophuhliso olukhawulezayo lwesayensi kunye nethekhinoloji, sifuna ukucinga okucacileyo kunye nobuchule bokuqonda obusebenzayo kunangaphambili. Isiphumo sokuphucula ingqondo ye-Nicotine isivulele umnyango omtsha, kodwa indlela yokuyisebenzisa ngokukhuselekileyo esi siphumo isafuna uphando olunzulu kunye nolawulo olungqongqo. Mhlawumbi kwixesha elizayo, siya kufumana indlela yokukhupha zombini izibonelelo ze-nicotine kwaye siphephe imingcipheko yayo, ukuze le nto ingaqondwa kakuhle ikwazi ukukhonza ukuqonda komntu ngokwenene.